“To Live & Die in L.A.” is the second single from Tupac Shakur’s final album he worked on during his life, The Don Killuminati: The 7 Day Theory. It was produced by QD3, son of producer Quincy Jones. The radio edit was recorded the same day and a video was shot. The album version contains a Dr. Dre diss at the end of the song. The clean version has altered lyrics and is longer. The single peaked number 82 Netherlands and 9 New Zealand, number 10 in the UK and on the UK R&B chart number 2.
A music video was shot. It features Shakur working at a fruit stand, driving around Los Angeles in a car filled with women, and also features various scenes and pictures of notable places and events in Los Angeles. The video can be found on the DualDisc of The Don Killuminati: The 7 Day Theory, and was the first video shot for the album as well as one of the last videos that Tupac filmed before his death.